Actin cytoskeleton: Thinking globally, actin’ locally
Author(s)Lanier, Lorene M.; Gertler, Frank
MetadataShow full item record
A class of proteins dubbed pipmodulins bind to and sequester the phospholipid PIP2 in the plasma membrane. Local release of PIP2 controls actin dynamics in specific subcellular regions and plays a critical role in regulating actin-based cell motility and morphogenesis.
DepartmentMassachusetts Institute of Technology. Department of Biology
Lanier, Lorene M., and Frank B. Gertler. “Actin cytoskeleton: Thinking globally, actin’ locally.” Current Biology 10, no. 18 (September 2000): R655-R657. Copyright © 2000 Elsevier Science Ltd.
Final published version