The Logic Linking Protein Acetylation and Metabolism
Author(s)Guarente, Leonard Pershing
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Protein acetylation now rivals phosphorylation in frequency of occurrence but is incompletely understood. A picture is presented in which protein acetylation is linked to available energy via the NAD-dependent deacetylases. This model suggests that protein acetylation regulates metabolic strategy and also helps store energy in cells.
DepartmentMassachusetts Institute of Technology. Department of Biology; Paul F. Glenn Center for Biology of Aging Research (Massachusetts Institute of Technology)
Guarente, Leonard. “The Logic Linking Protein Acetylation and Metabolism.” Cell Metabolism 14, no. 2 (August 2011): 151-153. Copyright © 2011 Elsevier Inc.
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