The Logic Linking Protein Acetylation and Metabolism

Author(s)
Guarente, Leonard Pershing
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Abstract
Protein acetylation now rivals phosphorylation in frequency of occurrence but is incompletely understood. A picture is presented in which protein acetylation is linked to available energy via the NAD-dependent deacetylases. This model suggests that protein acetylation regulates metabolic strategy and also helps store energy in cells.
Date issued
2011-08
URI
http://hdl.handle.net/1721.1/84487
Department
Massachusetts Institute of Technology. Department of Biology; Paul F. Glenn Center for Biology of Aging Research (Massachusetts Institute of Technology)
Journal
Cell Metabolism
Publisher
Elsevier
Citation
Guarente, Leonard. “The Logic Linking Protein Acetylation and Metabolism.” Cell Metabolism 14, no. 2 (August 2011): 151-153. Copyright © 2011 Elsevier Inc.
Version: Final published version
ISSN
15504131
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