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NF-κB Fans the Flames of Lung Carcinogenesis

Author(s)
Wong, Kwok-Kin; Dranoff, Glenn; Jacks, Tyler E
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Abstract
This perspective on Deng et al. (beginning on p. 424 in this issue of the journal) examines the link between NF-κB and lung tumorigenesis. Experiments in genetically engineered mouse models of lung cancers are elucidating protumorigenic roles of NF-κB activation in lung cancer pathogenesis. Our growing understanding of the tumor-promoting NF-κB downstream effector pathways could lead to the development of novel approaches for lung cancer therapy and chemoprevention.
Date issued
2010-03
URI
http://hdl.handle.net/1721.1/84642
Department
Koch Institute for Integrative Cancer Research at MIT
Journal
Cancer Prevention Research
Publisher
American Association for Cancer Research
Citation
Wong, K. K., T. Jacks, and G. Dranoff. “NF- B Fans the Flames of Lung Carcinogenesis.” Cancer Prevention Research 3, no. 4 (April 4, 2010): 403-405.
Version: Author's final manuscript
ISSN
1940-6207
1940-6215

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