The Cancer Genome Atlas Pan-Cancer analysis project
Author(s)
Park, Peter J.; Lander, Eric Steven
DownloadLander_The cancer genome.pdf (608.1Kb)
PUBLISHER_CC
Publisher with Creative Commons License
Creative Commons Attribution
Terms of use
Metadata
Show full item recordAbstract
The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile.
Date issued
2013-09Department
Massachusetts Institute of Technology. Department of BiologyJournal
Nature Genetics
Publisher
Nature Publishing Group
Citation
Chang, Kyle, Chad J Creighton, Caleb Davis, Lawrence Donehower, Jennifer Drummond, David Wheeler, Adrian Ally, et al. “The Cancer Genome Atlas Pan-Cancer analysis project.” Nature Genetics 45, no. 10 (September 26, 2013): 1113-1120.
Version: Final published version
ISSN
1061-4036
1546-1718