| dc.contributor.author | Biscoe, Mark R. | |
| dc.contributor.author | Fors, Brett P. | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2014-05-15T18:39:46Z | |
| dc.date.available | 2014-05-15T18:39:46Z | |
| dc.date.issued | 2008-05 | |
| dc.date.submitted | 2008-02 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/87011 | |
| dc.description.abstract | A new class of one-component Pd precatalysts bearing biarylphosphine ligands is described. These precatalysts are air- and thermally stable, are easily activated under normal reaction conditions at or below room temperature, and ensure the formation of the highly active monoligated Pd(0) complex necessary for oxidative addition. The use of these precatalysts as a convenient source of LPd(0) in C−N cross-coupling reactions is explored. The reactivity that is demonstrated in this study is unprecedented in palladium chemistry. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (GM-058160) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (postdoctoral fellowship (GM-F32-75685)) | en_US |
| dc.description.sponsorship | Boehringer Ingelheim Pharmaceuticals | en_US |
| dc.description.sponsorship | Merck Research Laboratories | en_US |
| dc.description.sponsorship | Amgen Inc. | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ja801137k | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | ACS | en_US |
| dc.title | A New Class of Easily Activated Palladium Precatalysts for Facile C−N Cross-Coupling Reactions and the Low Temperature Oxidative Addition of Aryl Chlorides | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Biscoe, Mark R., Brett P. Fors, and Stephen L. Buchwald. “A New Class of Easily Activated Palladium Precatalysts for Facile C−N Cross-Coupling Reactions and the Low Temperature Oxidative Addition of Aryl Chlorides.” Journal of the American Chemical Society 130, no. 21 (May 2008): 6686–6687. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Biscoe, Mark R. | en_US |
| dc.contributor.mitauthor | Fors, Brett P. | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Journal of the American Chemical Society | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Biscoe, Mark R.; Fors, Brett P.; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
