dc.contributor.author | Mellios, Nikolaos | |
dc.contributor.author | Sur, Mriganka | |
dc.date.accessioned | 2014-06-23T16:02:37Z | |
dc.date.available | 2014-06-23T16:02:37Z | |
dc.date.issued | 2012-04 | |
dc.identifier.issn | 1664-0640 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/88062 | |
dc.description.abstract | MicroRNAs (miRNAs) are small non-coding RNAs conserved throughout evolution whose perceived importance for brain development and maturation is increasingly being understood. Although a plethora of new discoveries have provided novel insights into miRNA-mediated molecular mechanisms that influence brain plasticity, their relevance for neuropsychiatric diseases with known deficits in synaptic plasticity, such as schizophrenia and autism, has not been adequately explored. In this review we discuss the intersection between current and old knowledge on the role of miRNAs in brain plasticity and function with a focus in the potential involvement of brain expressed miRNAs in the pathophysiology of neuropsychiatric disorders. | en_US |
dc.language.iso | en_US | |
dc.publisher | Frontiers Research Foundation | en_US |
dc.relation.isversionof | http://dx.doi.org/10.3389/fpsyt.2012.00039 | en_US |
dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
dc.source | Frontiers Research Foundation | en_US |
dc.title | The Emerging Role of microRNAs in Schizophrenia and Autism Spectrum Disorders | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Mellios, Nikolaos, and Mriganka Sur. “The Emerging Role of microRNAs in Schizophrenia and Autism Spectrum Disorders.” Frontiers in Psychiatry 3 (2012). | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences | en_US |
dc.contributor.department | Picower Institute for Learning and Memory | en_US |
dc.contributor.mitauthor | Mellios, Nikolaos | en_US |
dc.contributor.mitauthor | Sur, Mriganka | en_US |
dc.relation.journal | Frontiers in Psychiatry | en_US |
dc.eprint.version | Final published version | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.orderedauthors | Mellios, Nikolaos; Sur, Mriganka | en_US |
dc.identifier.orcid | https://orcid.org/0000-0003-2442-5671 | |
mit.license | PUBLISHER_POLICY | en_US |
mit.metadata.status | Complete | |