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dc.contributor.authorRusconi, Roberto
dc.contributor.authorStocker, Roman
dc.contributor.authorGarren, Melissa
dc.date.accessioned2014-09-15T16:24:01Z
dc.date.available2014-09-15T16:24:01Z
dc.date.issued2014-05
dc.identifier.issn1936-122X
dc.identifier.issn1936-1238
dc.identifier.urihttp://hdl.handle.net/1721.1/89527
dc.description.abstractMicrofluidics has significantly contributed to the expansion of the frontiers of microbial ecology over the past decade by allowing researchers to observe the behaviors of microbes in highly controlled microenvironments, across scales from a single cell to mixed communities. Spatially and temporally varying distributions of organisms and chemical cues that mimic natural microbial habitats can now be established by exploiting physics at the micrometer scale and by incorporating structures with specific geometries and materials. In this article, we review applications of microfluidics that have resulted in insightful discoveries on fundamental aspects of microbial life, ranging from growth and sensing to cell-cell interactions and population dynamics. We anticipate that this flexible multidisciplinary technology will continue to facilitate discoveries regarding the ecology of microorganisms and help uncover strategies to control microbial processes such as biofilm formation and antibiotic resistance.en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (Grant OCE-0744641-CAREER)en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (Grant IOS-1120200)en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (Grant CBET-1066566)en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (Grant CBET-0966000)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (NIH grant 1R01GM100473-0)en_US
dc.description.sponsorshipHuman Frontier Science Program (Strasbourg, France)en_US
dc.description.sponsorshipHuman Frontier Science Program (Strasbourg, France) (award RGY0089)en_US
dc.description.sponsorshipGordon and Betty Moore Foundation (Microbial Initiative Investigator Award)en_US
dc.language.isoen_US
dc.publisherAnnual Reviewsen_US
dc.relation.isversionofhttp://dx.doi.org/10.1146/annurev-biophys-051013-022916en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourcePMCen_US
dc.titleMicrofluidics Expanding the Frontiers of Microbial Ecologyen_US
dc.typeArticleen_US
dc.identifier.citationRusconi, Roberto, Melissa Garren, and Roman Stocker. “Microfluidics Expanding the Frontiers of Microbial Ecology.” Annu. Rev. Biophys. 43, no. 1 (May 6, 2014): 65–91.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Civil and Environmental Engineeringen_US
dc.contributor.departmentParsons Laboratory for Environmental Science and Engineering (Massachusetts Institute of Technology)en_US
dc.contributor.mitauthorRusconi, Robertoen_US
dc.contributor.mitauthorGarren, Melissa S.en_US
dc.contributor.mitauthorStocker, Romanen_US
dc.relation.journalAnnual Review of Biophysicsen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsRusconi, Roberto; Garren, Melissa; Stocker, Romanen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-3199-0508
mit.licenseOPEN_ACCESS_POLICYen_US
mit.metadata.statusComplete


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