dc.contributor.author | Rusconi, Roberto | |
dc.contributor.author | Stocker, Roman | |
dc.contributor.author | Garren, Melissa | |
dc.date.accessioned | 2014-09-15T16:24:01Z | |
dc.date.available | 2014-09-15T16:24:01Z | |
dc.date.issued | 2014-05 | |
dc.identifier.issn | 1936-122X | |
dc.identifier.issn | 1936-1238 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/89527 | |
dc.description.abstract | Microfluidics has significantly contributed to the expansion of the frontiers of microbial ecology over the past decade by allowing researchers to observe the behaviors of microbes in highly controlled microenvironments, across scales from a single cell to mixed communities. Spatially and temporally varying distributions of organisms and chemical cues that mimic natural microbial habitats can now be established by exploiting physics at the micrometer scale and by incorporating structures with specific geometries and materials. In this article, we review applications of microfluidics that have resulted in insightful discoveries on fundamental aspects of microbial life, ranging from growth and sensing to cell-cell interactions and population dynamics. We anticipate that this flexible multidisciplinary technology will continue to facilitate discoveries regarding the ecology of microorganisms and help uncover strategies to control microbial processes such as biofilm formation and antibiotic resistance. | en_US |
dc.description.sponsorship | National Science Foundation (U.S.) (Grant OCE-0744641-CAREER) | en_US |
dc.description.sponsorship | National Science Foundation (U.S.) (Grant IOS-1120200) | en_US |
dc.description.sponsorship | National Science Foundation (U.S.) (Grant CBET-1066566) | en_US |
dc.description.sponsorship | National Science Foundation (U.S.) (Grant CBET-0966000) | en_US |
dc.description.sponsorship | National Institutes of Health (U.S.) (NIH grant 1R01GM100473-0) | en_US |
dc.description.sponsorship | Human Frontier Science Program (Strasbourg, France) | en_US |
dc.description.sponsorship | Human Frontier Science Program (Strasbourg, France) (award RGY0089) | en_US |
dc.description.sponsorship | Gordon and Betty Moore Foundation (Microbial Initiative Investigator Award) | en_US |
dc.language.iso | en_US | |
dc.publisher | Annual Reviews | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1146/annurev-biophys-051013-022916 | en_US |
dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
dc.source | PMC | en_US |
dc.title | Microfluidics Expanding the Frontiers of Microbial Ecology | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Rusconi, Roberto, Melissa Garren, and Roman Stocker. “Microfluidics Expanding the Frontiers of Microbial Ecology.” Annu. Rev. Biophys. 43, no. 1 (May 6, 2014): 65–91. | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering | en_US |
dc.contributor.department | Parsons Laboratory for Environmental Science and Engineering (Massachusetts Institute of Technology) | en_US |
dc.contributor.mitauthor | Rusconi, Roberto | en_US |
dc.contributor.mitauthor | Garren, Melissa S. | en_US |
dc.contributor.mitauthor | Stocker, Roman | en_US |
dc.relation.journal | Annual Review of Biophysics | en_US |
dc.eprint.version | Author's final manuscript | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.orderedauthors | Rusconi, Roberto; Garren, Melissa; Stocker, Roman | en_US |
dc.identifier.orcid | https://orcid.org/0000-0002-3199-0508 | |
mit.license | OPEN_ACCESS_POLICY | en_US |
mit.metadata.status | Complete | |