Fabrication of a Hybrid Microfluidic System Incorporating both Lithographically Patterned Microchannels and a 3D Fiber-Formed Microfluidic Network
Author(s)Bellan, Leon M.; Kniazeva, Tatiana; Kim, Ernest S.; Epshteyn, Alla A.; Cropek, Donald M.; Borenstein, Jeffrey T.; Langer, Robert S; ... Show more Show less
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A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels.
DepartmentCharles Stark Draper Laboratory; Massachusetts Institute of Technology. Center for Biomedical Engineering; Koch Institute for Integrative Cancer Research at MIT
Advanced Healthcare Materials
Wiley-VCH Verlag GmbH & Co.
Bellan, Leon M., Tatiana Kniazeva, Ernest S. Kim, Alla A. Epshteyn, Donald M. Cropek, Robert Langer, and Jeffrey T. Borenstein. “Fabrication of a Hybrid Microfluidic System Incorporating Both Lithographically Patterned Microchannels and a 3D Fiber-Formed Microfluidic Network.” Advanced Healthcare Materials 1, no. 2 (January 20, 2012): 164–167.
Author's final manuscript