Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes

Author(s)
Zhu, Rong; Buchwald, Stephen Leffler
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Abstract
A mild, versatile, and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes based on a copper-catalyzed oxidative difunctionalization strategy has been developed. This methodology provides access to a variety of classes of synthetically useful CF[subscript 3]-containing building blocks from simple starting materials.
Date issued
2012-07
URI
http://hdl.handle.net/1721.1/94323
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Citation
Zhu, Rong, and Stephen L. Buchwald. “Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes.” Journal of the American Chemical Society 134, no. 30 (August 2012): 12462–12465.
Version: Author's final manuscript
ISSN
0002-7863
1520-5126
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