Peptide-based targeting of fluorescent zinc sensors to the plasma membrane of live cells
Author(s)
Radford, Robert J.; Chyan, Wen; Lippard, Stephen J.
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Combining fluorescent zinc sensors with the facile syntheses and biological targeting capabilities of peptides, we created green- and blue-emitting probes that (i) are readily prepared on the solid-phase, (ii) retain the photophysical and zinc-binding properties of the parent sensor, and (iii) can be directed to the extracellular side of plasma membranes in live cells for detection of mobile zinc.
Date issued
2013-05Department
Massachusetts Institute of Technology. Department of ChemistryJournal
Chemical Science
Publisher
Royal Society of Chemistry, The
Citation
Radford, Robert J., Wen Chyan, and Stephen J. Lippard. “Peptide-Based Targeting of Fluorescent Zinc Sensors to the Plasma Membrane of Live Cells.” Chemical Science 4, no. 8 (2013): 3080. © 2013 Royal Society of Chemistry
Version: Author's final manuscript
ISSN
2041-6520
2041-6539