Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation
Author(s)Chou, Song; Chu, Pat; Hwang, William; Lodish, Harvey F.
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A recent Science paper reported a purine derivative that expands human cord blood hematopoietic stem cells in culture ( Boitano et al., 2010) by antagonizing the aryl hydrocarbon receptor. Major problems need to be overcome before ex vivo HSC expansion can be used clinically.
DepartmentMassachusetts Institute of Technology. Department of Biology; Whitehead Institute for Biomedical Research
Cell Stem Cell
Chou, Song, Pat Chu, William Hwang, and Harvey Lodish. “Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation.” Cell Stem Cell 7, no. 4 (October 2010): 427–428. © 2010 Elsevier B.V.
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