MicroRNAs: Target Recognition and Regulatory Functions
Author(s)
Bartel, David
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MicroRNAs (miRNAs) are endogenous ∼23 nt RNAs that play important gene-regulatory roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their posttranscriptional repression. This review outlines the current understanding of miRNA target recognition in animals and discusses the widespread impact of miRNAs on both the expression and evolution of protein-coding genes.
Date issued
2009-01Department
Massachusetts Institute of Technology. Department of Biology; Whitehead Institute for Biomedical ResearchJournal
Cell
Publisher
Elsevier B.V.
Citation
Bartel, David P. “MicroRNAs: Target Recognition and Regulatory Functions.” Cell 136, no. 2 (January 2009): 215–233. © 2009 Elsevier Inc.
Version: Final published version
ISSN
00928674