MicroRNAs: Target Recognition and Regulatory Functions
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MicroRNAs (miRNAs) are endogenous ∼23 nt RNAs that play important gene-regulatory roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their posttranscriptional repression. This review outlines the current understanding of miRNA target recognition in animals and discusses the widespread impact of miRNAs on both the expression and evolution of protein-coding genes.
DepartmentMassachusetts Institute of Technology. Department of Biology; Whitehead Institute for Biomedical Research
Bartel, David P. “MicroRNAs: Target Recognition and Regulatory Functions.” Cell 136, no. 2 (January 2009): 215–233. © 2009 Elsevier Inc.
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