Unraveling Tumor Suppressor Networks with In Vivo RNAi
Author(s)Braun, Christian Joerg; Hemann, Michael
MetadataShow full item record
BMI1 is a known oncogenic transcriptional repressor in glioblastoma stem-like cells, but its downstream mediators are poorly understood. Recently, in Cancer Cell, Gargiulo et al. (2013) designed a rational in vivo RNAi screen based on BMI1 ChIP-seq from neural progenitors and identified functional tumor suppressor targets, including Atf3 and Cbx7.
DepartmentDavid H. Koch Institute for Integrative Cancer Research at MIT; Massachusetts Institute of Technology. Department of Biology
Cell Stem Cell
Braun, Christian J., and Michael T. Hemann. “Unraveling Tumor Suppressor Networks with In Vivo RNAi.” Cell Stem Cell 12, no. 6 (June 2013): 639–641. © 2013 Elsevier Inc.
Final published version