Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents

Author(s)
Zhu, Ye; Buchwald, Stephen Leffler
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Abstract
A palladium-catalyzed asymmetric arylation of 9-aminofluorene-derived imines using a chiral dialkylbiaryl phosphine as the supporting ligand has been developed. This transformation allows for enantioselective access to a diverse range of α-branched benzylamines.
Date issued
2014-03
URI
http://hdl.handle.net/1721.1/96508
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Citation
Zhu, Ye, and Stephen L. Buchwald. “Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents.” Journal of the American Chemical Society 136, no. 12 (March 26, 2014): 4500–4503. © 2014 American Chemical Society
Version: Final published version
ISSN
0002-7863
1520-5126
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