dc.contributor.author | Goodman, Aaron Jacob | |
dc.contributor.author | Tisdale, William A. | |
dc.date.accessioned | 2015-05-07T15:27:56Z | |
dc.date.available | 2015-05-07T15:27:56Z | |
dc.date.issued | 2015-05 | |
dc.date.submitted | 2014-12 | |
dc.identifier.issn | 0031-9007 | |
dc.identifier.issn | 1079-7114 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/96930 | |
dc.description.abstract | Second-order nonlinear optical interactions such as sum- and difference-frequency generation are widely used for bioimaging and as selective probes of interfacial environments. However, inefficient nonlinear optical conversion often leads to poor signal-to-noise ratio and long signal acquisition times. Here, we demonstrate the dramatic enhancement of weak second-order nonlinear optical signals via stimulated sum- and difference-frequency generation. We present a conceptual framework to quantitatively describe the interaction and show that the process is highly sensitive to the relative optical phase of the stimulating field. To emphasize the utility of the technique, we demonstrate stimulated enhancement of second harmonic generation (SHG) from bovine collagen-I fibrils. Using a stimulating pulse fluence of only 3 nJ/cm[superscript 2], we obtain an SHG enhancement > 10[superscript 4] relative to the spontaneous signal. The stimulation enhancement is greatest in situations where spontaneous signals are the weakest—such as low laser power, small sample volume, and weak nonlinear susceptibility—emphasizing the potential for this technique to improve signal-to-noise ratios in biological imaging and interfacial spectroscopy. | en_US |
dc.description.sponsorship | United States. Dept. of Energy. Office of Basic Energy Sciences (Award DE-SC0010538) | en_US |
dc.description.sponsorship | National Science Foundation (U.S.) (Grant 1122374) | en_US |
dc.publisher | American Physical Society | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1103/PhysRevLett.114.183902 | en_US |
dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
dc.source | American Physical Society | en_US |
dc.title | Enhancement of Second-Order Nonlinear-Optical Signals by Optical Stimulation | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Goodman, A. J., and W. A. Tisdale. "Enhancement of Second-Order Nonlinear-Optical Signals by Optical Stimulation." Phys. Rev. Lett. 114, 183902 (May 2015). © 2015 American Physical Society | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Chemical Engineering | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
dc.contributor.mitauthor | Goodman, Aaron Jacob | en_US |
dc.contributor.mitauthor | Tisdale, William A. | en_US |
dc.relation.journal | Physical Review Letters | en_US |
dc.eprint.version | Final published version | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dc.date.updated | 2015-05-06T22:00:02Z | |
dc.language.rfc3066 | en | |
dc.rights.holder | American Physical Society | |
dspace.orderedauthors | Goodman, A. J.; Tisdale, W. A. | en_US |
dc.identifier.orcid | https://orcid.org/0000-0002-6615-5342 | |
dc.identifier.orcid | https://orcid.org/0000-0002-0159-5646 | |
mit.license | PUBLISHER_POLICY | en_US |
mit.metadata.status | Complete | |