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Three-Dimensional Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

Author(s)
Hong, Sungmin; Sycks, Dalton; Chan, Hon Fai; Lin, Shaoting; Lopez, Gabriel P.; Guilak, Farshid; Leong, Kam W.; Zhao, Xuanhe; ... Show more Show less
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Alternative title
3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures
Terms of use
Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/
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Abstract
A 3D printable and highly stretchable tough hydrogel is developed by combining poly(ethylene glycol) and sodium alginate, which synergize to form a hydrogel tougher than natural cartilage. Encapsulated cells maintain high viability over a 7 d culture period and are highly deformed together with the hydrogel. By adding biocompatible nanoclay, the tough hydrogel is 3D printed in various shapes without requiring support material.
Date issued
2015-05
URI
http://hdl.handle.net/1721.1/97186
Department
Massachusetts Institute of Technology. Department of Civil and Environmental Engineering; Massachusetts Institute of Technology. Department of Mechanical Engineering
Journal
Advanced Materials
Publisher
Wiley Blackwell
Citation
Hong, Sungmin et al. “3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.” Advanced Materials (2015): n/a–n/a.
Version: Author's final manuscript
ISSN
09359648
1521-4095

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