dc.contributor.author | Bruno, Nicholas C. | |
dc.contributor.author | Niljianskul, Nootaree | |
dc.contributor.author | Buchwald, Stephen Leffler | |
dc.date.accessioned | 2015-06-19T14:57:15Z | |
dc.date.available | 2015-06-19T14:57:15Z | |
dc.date.issued | 2014-04 | |
dc.date.submitted | 2014-02 | |
dc.identifier.issn | 0022-3263 | |
dc.identifier.issn | 1520-6904 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/97471 | |
dc.description.abstract | A series of phosphine-ligated palladium precatalysts based on N-methyl- and N-phenyl-2-aminobiphenyl have been developed. Substitution at the nitrogen center prevents the presence of traces of aminobiphenyls that contain a free −NH[subscript 2] group from contaminating cross-coupling products. These precatalysts produce N-substituted carbazoles upon activation, which cannot consume starting materials. These precatalysts were efficiently generated from 2-aminobiphenyl with minimal purification and found to be highly effective in Suzuki–Miyaura and C–N cross-coupling reactions. | en_US |
dc.description.sponsorship | National Institutes of Health (U.S.) (GM46059) | en_US |
dc.description.sponsorship | National Institutes of Health (U.S.) (GM58160) | en_US |
dc.language.iso | en_US | |
dc.relation.isversionof | http://dx.doi.org/10.1021/jo500355k | en_US |
dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
dc.source | American Chemical Society | en_US |
dc.title | N-Substituted 2-Aminobiphenylpalladium Methanesulfonate Precatalysts and Their Use in C–C and C–N Cross-Couplings | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Bruno, Nicholas C., Nootaree Niljianskul, and Stephen L. Buchwald. “N-Substituted 2-Aminobiphenylpalladium Methanesulfonate Precatalysts and Their Use in C–C and C–N Cross-Couplings.” The Journal of Organic Chemistry 79, no. 9 (May 2, 2014): 4161–4166. © 2014 American Chemical Society | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
dc.contributor.mitauthor | Bruno, Nicholas C. | en_US |
dc.contributor.mitauthor | Niljianskul, Nootaree | en_US |
dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
dc.relation.journal | The Journal of Organic Chemistry | en_US |
dc.eprint.version | Final published version | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.orderedauthors | Bruno, Nicholas C.; Niljianskul, Nootaree; Buchwald, Stephen L. | en_US |
dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
mit.license | PUBLISHER_POLICY | en_US |
mit.metadata.status | Complete | |