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dc.contributor.authorBruno, Nicholas C.
dc.contributor.authorNiljianskul, Nootaree
dc.contributor.authorBuchwald, Stephen Leffler
dc.date.accessioned2015-06-19T14:57:15Z
dc.date.available2015-06-19T14:57:15Z
dc.date.issued2014-04
dc.date.submitted2014-02
dc.identifier.issn0022-3263
dc.identifier.issn1520-6904
dc.identifier.urihttp://hdl.handle.net/1721.1/97471
dc.description.abstractA series of phosphine-ligated palladium precatalysts based on N-methyl- and N-phenyl-2-aminobiphenyl have been developed. Substitution at the nitrogen center prevents the presence of traces of aminobiphenyls that contain a free −NH[subscript 2] group from contaminating cross-coupling products. These precatalysts produce N-substituted carbazoles upon activation, which cannot consume starting materials. These precatalysts were efficiently generated from 2-aminobiphenyl with minimal purification and found to be highly effective in Suzuki–Miyaura and C–N cross-coupling reactions.en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (GM46059)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (GM58160)en_US
dc.language.isoen_US
dc.relation.isversionofhttp://dx.doi.org/10.1021/jo500355ken_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourceAmerican Chemical Societyen_US
dc.titleN-Substituted 2-Aminobiphenylpalladium Methanesulfonate Precatalysts and Their Use in C–C and C–N Cross-Couplingsen_US
dc.typeArticleen_US
dc.identifier.citationBruno, Nicholas C., Nootaree Niljianskul, and Stephen L. Buchwald. “N-Substituted 2-Aminobiphenylpalladium Methanesulfonate Precatalysts and Their Use in C–C and C–N Cross-Couplings.” The Journal of Organic Chemistry 79, no. 9 (May 2, 2014): 4161–4166. © 2014 American Chemical Societyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.mitauthorBruno, Nicholas C.en_US
dc.contributor.mitauthorNiljianskul, Nootareeen_US
dc.contributor.mitauthorBuchwald, Stephen Leffleren_US
dc.relation.journalThe Journal of Organic Chemistryen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsBruno, Nicholas C.; Niljianskul, Nootaree; Buchwald, Stephen L.en_US
dc.identifier.orcidhttps://orcid.org/0000-0003-3875-4775
mit.licensePUBLISHER_POLICYen_US
mit.metadata.statusComplete


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