Oxygen levels in thermoplastic microfluidic devices during cell culture

Author(s)
Ochs, Christopher J.; Kasuya, Junichi; Pavesi, Andrea; Kamm, Roger Dale
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Abstract
We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation of oxygen levels. Conditions are determined that provide adequate oxygen supply to two cell types, hepatocytes and endothelial cells, either by diffusion through the plastic device, or by supplying a low flow rate of medium.
Date issued
2013-11
URI
http://hdl.handle.net/1721.1/97509
Department
Massachusetts Institute of Technology. Department of Biological Engineering
Journal
Lab on a Chip
Publisher
Royal Society of Chemistry
Citation
Ochs, Christopher J., Junichi Kasuya, Andrea Pavesi, and Roger D. Kamm. “Oxygen Levels in Thermoplastic Microfluidic Devices During Cell Culture.” Lab Chip 14, no. 3 (2014): 459–462.
Version: Author's final manuscript
ISSN
1473-0197
1473-0189
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