Interactome analysis brings splicing into focus

Author(s)
Dominguez, Daniel; Burge, Christopher B
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Abstract
The spliceosome is a huge molecular machine that assembles dynamically onto its pre-mRNA substrates. A new study based on interactome analysis provides clues about how splicing-regulatory proteins modulate assembly of the spliceosome to either activate or repress splicing.
Date issued
2015-07
URI
http://hdl.handle.net/1721.1/97693
Department
Massachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Department of Biology
Journal
Genome Biology
Publisher
BioMed Central
Citation
Dominguez, Daniel, and Christopher B. Burge. "Interactome analysis brings splicing into focus." Genome Biology. 2015 Jul 07;16(1):135.
Version: Final published version
ISSN
1465-6906
1474-7596
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