Interactome analysis brings splicing into focus
Author(s)
Dominguez, Daniel; Burge, Christopher B
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The spliceosome is a huge molecular machine that assembles dynamically onto its pre-mRNA substrates. A new study based on interactome analysis provides clues about how splicing-regulatory proteins modulate assembly of the spliceosome to either activate or repress splicing.
Date issued
2015-07Department
Massachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Department of BiologyJournal
Genome Biology
Publisher
BioMed Central
Citation
Dominguez, Daniel, and Christopher B. Burge. "Interactome analysis brings splicing into focus." Genome Biology. 2015 Jul 07;16(1):135.
Version: Final published version
ISSN
1465-6906
1474-7596