Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

Author(s)
Miyamoto, Kei; Allen, George E.; Jullien, Jerome; Otani, Tomoki; Bradshaw, Charles R.; ... Show more
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Abstract
Miyamoto et al. show genome-wide changes in chromatin accessibility during transcriptional reprogramming in oocytes using the frog nuclear transfer system. They demonstrate that donor cell chromatin states affect transcriptional reprogramming and changes in open chromatin during reprogramming are associated with specific transcription factors. Keywords: open chromatin; transcriptional activation; reprogramming; nuclear transfer
Date issued
2018-07
URI
http://hdl.handle.net/1721.1/117522
Department
Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory; Massachusetts Institute of Technology. Department of Biological Engineering
Journal
Cell Reports
Publisher
Elsevier
Citation
Miyamoto, Kei et al. “Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.” Cell Reports 24, 2 (July 2018): 304–311
Version: Final published version
ISSN
2211-1247
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