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Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

dc.contributor.authorMiyamoto, Kei
dc.contributor.authorAllen, George E.
dc.contributor.authorJullien, Jerome
dc.contributor.authorOtani, Tomoki
dc.contributor.authorBradshaw, Charles R.
dc.contributor.authorLivesey, Frederick J.
dc.contributor.authorGurdon, John B.
dc.contributor.authorNguyen, Khoi Thien
dc.contributor.authorKumar, Dinesh
dc.contributor.authorKellis, Manolis
dc.date.accessioned2018-08-24T18:46:09Z
dc.date.available2018-08-24T18:46:09Z
dc.date.issued2018-07
dc.date.submitted2018-03
dc.identifier.issn2211-1247
dc.identifier.urihttp://hdl.handle.net/1721.1/117522
dc.description.abstractMiyamoto et al. show genome-wide changes in chromatin accessibility during transcriptional reprogramming in oocytes using the frog nuclear transfer system. They demonstrate that donor cell chromatin states affect transcriptional reprogramming and changes in open chromatin during reprogramming are associated with specific transcription factors. Keywords: open chromatin; transcriptional activation; reprogramming; nuclear transferen_US
dc.publisherElsevieren_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.celrep.2018.06.030en_US
dc.rightsCreative Commons Attribution 4.0 International Licenseen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.sourceElsevieren_US
dc.titleChromatin Accessibility Impacts Transcriptional Reprogramming in Oocytesen_US
dc.typeArticleen_US
dc.identifier.citationMiyamoto, Kei et al. “Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.” Cell Reports 24, 2 (July 2018): 304–311en_US
dc.contributor.departmentMassachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratoryen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biological Engineeringen_US
dc.contributor.mitauthorNguyen, Khoi Thien
dc.contributor.mitauthorKumar, Dinesh
dc.contributor.mitauthorKellis, Manolis
dc.relation.journalCell Reportsen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2018-08-24T14:47:28Z
dspace.orderedauthorsMiyamoto, Kei; Nguyen, Khoi T.; Allen, George E.; Jullien, Jerome; Kumar, Dinesh; Otani, Tomoki; Bradshaw, Charles R.; Livesey, Frederick J.; Kellis, Manolis; Gurdon, John B.en_US
dspace.embargo.termsNen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-3908-3048
dc.identifier.orcidhttps://orcid.org/0000-0002-4925-4699
mit.licensePUBLISHER_CCen_US


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