Browsing MIT Open Access Articles by Title
Now showing items 4057-4076 of 55933
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Bioinformatics for the human microbiome project
(Public Library of Science, 2012-11)Microbes inhabit virtually all sites of the human body, yet we know very little about the role they play in our health. In recent years, there has been increasing interest in studying human-associated microbial communities, ... -
Bioinorganic Explorations of Zn(II) Sequestration by Human S100 Host-Defense Proteins
(American Chemical Society (ACS), 2018-01)The human innate immune system launches a metal-withholding response to starve invading microbial pathogens of essential metal nutrients. Zn(II)-sequestering proteins of the human S100 family contribute to this process and ... -
BioInsights: Extracting personal data from "Still" wearable motion sensors
(Institute of Electrical and Electronics Engineers (IEEE), 2015-06)During recent years a large variety of wearable devices have become commercially available. As these devices are in close contact with the body, they have the potential to capture sensitive and unexpected personal data ... -
Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
(Wiley Blackwell, 2016-02)Thousands of human diseases could be treated by selectively controlling the expression of specific proteins in vivo. A new series of alkenyl amino alcohol (AAA) ionizable lipid nanoparticles (LNPs) capable of delivering ... -
A bioinspired approach to engineer seed microenvironment to boost germination and mitigate soil salinity
(Proceedings of the National Academy of Sciences, 2019-11)© 2019 National Academy of Sciences. All rights reserved. Human population growth, soil degradation, and agrochemical misuse are significant challenges that agriculture must face in the upcoming decades as it pertains to ... -
Bioinspired chemistry at MOF secondary building units
(Royal Society of Chemistry (RSC), 2020-01)The secondary building units (SBUs) in metal-organic frameworks (MOFs) support metal ions in well-defined and site-isolated coordination environments with ligand fields similar to those found in metalloenzymes. This ... -
Bioinspired design of flexible armor based on chiton scales
(Springer Science and Business Media LLC, 2019-12)Man-made armors often rely on rigid structures for mechanical protection, which typically results in a trade-off with flexibility and maneuverability. Chitons, a group of marine mollusks, evolved scaled armors that address ... -
A bioinspired gelatin-hyaluronic acid-based hybrid interpenetrating network for the enhancement of retinal ganglion cells replacement therapy
(Springer Science and Business Media LLC, 2021)<jats:title>Abstract</jats:title><jats:p>Biomaterial-based cell replacement approaches to regenerative medicine are emerging as promising treatments for a wide array of profound clinical problems. Here we report an ... -
A bioinspired gelatin-hyaluronic acid-based hybrid interpenetrating network for the enhancement of retinal ganglion cells replacement therapy
(Springer Science and Business Media LLC, 2021-12)<jats:title>Abstract</jats:title><jats:p>Biomaterial-based cell replacement approaches to regenerative medicine are emerging as promising treatments for a wide array of profound clinical problems. Here we report an ... -
Bioinspired hierarchical composite design using machine learning: simulation, additive manufacturing, and experiment
(2018-07)Biomimicry, adapting and implementing nature's designs provides an adequate first-order solution to achieving superior mechanical properties. However, the design space is too vast even using biomimetic designs as prototypes ... -
Bioinspired kirigami metasurfaces as assistive shoe grips
(Springer Science and Business Media LLC, 2020)© 2020, The Author(s), under exclusive licence to Springer Nature Limited. Falls and subsequent complications are major contributors to morbidity and mortality, especially in older adults. Here, by taking inspiration from ... -
Bioinspired Materials for Controlling Stem Cell Fate
(American Chemical Society (ACS), 2010)Although researchers currently have limited ability to mimic the natural stem cell microenvironment, recent work at the interface of stem biology and biomaterials science has demonstrated that control over stem cell behavior ... -
Bioinspired metagel with broadband tunable impedance matching
(American Association for the Advancement of Science (AAAS), 2020)© 2020 The Authors, some rights reserved. To maximize energy transmission from a source through a media, the concept of impedance matching has been established in electrical, acoustic, and optical engineering. However, ... -
Bioinspired micrograting arrays mimicking the reverse color diffraction elements evolved by the butterfly Pierella luna
(National Academy of Sciences (U.S.), 2014-10)Recently, diffraction elements that reverse the color sequence normally observed in planar diffraction gratings have been found in the wing scales of the butterfly Pierella luna. Here, we describe the creation of an ... -
Bioinspired Multivalent DNA Network for Capture and Release of Cells
(National Academy of Sciences (U.S.), 2012-11)Capture and isolation of flowing cells and particulates from body fluids has enormous implications in diagnosis, monitoring, and drug testing, yet monovalent adhesion molecules used for this purpose result in inefficient ... -
Bioinspired Nanoparticulate Medical Glues for Minimally Invasive Tissue Repair
(Wiley Blackwell, 2015-11)Delivery of tissue glues through small-bore needles or trocars is critical for sealing holes, affixing medical devices, or attaching tissues together during minimally invasive surgeries. Inspired by the granule-packaged ... -
Bioinspired Security Analysis of Wireless Protocols
(Springer US, 2016-03)Fraglets represent an execution model for communication protocols that resembles the chemical reactions in living organisms. The strong connection between their way of transforming and reacting and formal rewriting systems ... -
Bioinspired Ultra-Low Adhesive Energy Interface for Continuous 3D Printing: Reducing Curing Induced Adhesion
(American Association for the Advancement of Science (AAAS), 2018-12)Additive manufacturing based on liquid resin curing is one of the most promising methods to construct delicate structures. However, precision and speed are limited by the vertical adhesion of in situ cured resin at the ... -
Bioinspired, ingestible electroceutical capsules for hunger-regulating hormone modulation
(American Association for the Advancement of Science, 2023-04-26)The gut-brain axis, which is mediated via enteric and central neurohormonal signaling, is known to regulate a broad set of physiological functions from feeding to emotional behavior. Various pharmaceuticals and surgical ... -
Bioinspired, mechanical, deterministic fractal model for hierarchical suture joints
(American Physical Society, 2012-03)Many biological systems possess hierarchical and fractal-like interfaces and joint structures that bear and transmit loads, absorb energy, and accommodate growth, respiration, and/or locomotion. In this paper, an elastic ...
