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Effect of sequence features on assembly of spider silk block copolymers

dc.contributor.authorTokareva, Olena S.
dc.contributor.authorLin, Shangchao
dc.contributor.authorJacobsen, Matthew M.
dc.contributor.authorHuang, Wenwen
dc.contributor.authorRizzo, Daniel
dc.contributor.authorLi, David
dc.contributor.authorSimon, Marc
dc.contributor.authorStaii, Cristian
dc.contributor.authorCebe, Peggy
dc.contributor.authorWong, Joyce Y.
dc.contributor.authorBuehler, Markus J.
dc.contributor.authorKaplan, David L.
dc.contributor.authorBuehler, Markus J.
dc.date.accessioned2016-03-04T15:32:53Z
dc.date.available2016-03-04T15:32:53Z
dc.date.issued2014-03
dc.date.submitted2014-03
dc.identifier.issn10478477
dc.identifier.issn1095-8657
dc.identifier.urihttp://hdl.handle.net/1721.1/101597
dc.description.abstractBioengineered spider silk block copolymers were studied to understand the effect of protein chain length and sequence chemistry on the formation of secondary structure and materials assembly. Using a combination of in vitro protein design and assembly studies, we demonstrate that silk block copolymers possessing multiple repetitive units self-assemble into lamellar microstructures. Additionally, the study provides insights into the assembly behavior of spider silk block copolymers in concentrated salt solutions.en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (NIH U01 EB014976)en_US
dc.language.isoen_US
dc.publisherElsevieren_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.jsb.2014.03.004en_US
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs Licenseen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.sourcePMCen_US
dc.titleEffect of sequence features on assembly of spider silk block copolymersen_US
dc.typeArticleen_US
dc.identifier.citationTokareva, Olena S., Shangchao Lin, Matthew M. Jacobsen, Wenwen Huang, Daniel Rizzo, David Li, Marc Simon, et al. “Effect of Sequence Features on Assembly of Spider Silk Block Copolymers.” Journal of Structural Biology 186, no. 3 (June 2014): 412–419.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Civil and Environmental Engineeringen_US
dc.contributor.mitauthorLin, Shangchaoen_US
dc.contributor.mitauthorBuehler, Markus J.en_US
dc.relation.journalJournal of Structural Biologyen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsTokareva, Olena S.; Lin, Shangchao; Jacobsen, Matthew M.; Huang, Wenwen; Rizzo, Daniel; Li, David; Simon, Marc; Staii, Cristian; Cebe, Peggy; Wong, Joyce Y.; Buehler, Markus J.; Kaplan, David L.en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-4173-9659
mit.licensePUBLISHER_CCen_US


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