Identification and Manipulation of Memory Engram Cells

Author(s)
Liu, Xu; Ramirez Moreno, Steve; Tonegawa, Susumu; Redondo, Roger L.
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Abstract
How memories are formed and stored in the brain remains a fascinating question in neuroscience. Here we discuss the memory engram theory, our recent attempt to identify and manipulate memory engram cells in the brain with optogenetics, and how these methods are used to address questions such as how false memory is formed and how the valence of a memory can be changed in the brain.
Date issued
2014
URI
http://hdl.handle.net/1721.1/106800
Department
Massachusetts Institute of Technology. Department of Biology; Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences; Picower Institute for Learning and Memory; RIKEN-MIT Center for Neural Circuit Genetics
Journal
Cold Spring Harbor Symposia on Quantitative Biology
Publisher
Cold Spring Harbor Laboratory Press
Citation
Liu, Xu, Steve Ramirez, Roger L. Redondo, and Susumu Tonegawa. “Identification and Manipulation of Memory Engram Cells.” Cold Spring Harbor Symposia on Quantitative Biology 79 (2014): 59–65.
Version: Author's final manuscript
ISSN
0091-7451
1943-4456
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