| dc.contributor.author | Liu, Xu |  | 
| dc.contributor.author | Ramirez Moreno, Steve |  | 
| dc.contributor.author | Tonegawa, Susumu |  | 
| dc.contributor.author | Redondo, Roger L. |  | 
| dc.date.accessioned | 2017-01-31T15:31:37Z |  | 
| dc.date.available | 2017-01-31T15:31:37Z |  | 
| dc.date.issued | 2014 |  | 
| dc.identifier.issn | 0091-7451 |  | 
| dc.identifier.issn | 1943-4456 |  | 
| dc.identifier.uri | http://hdl.handle.net/1721.1/106800 |  | 
| dc.description.abstract | How memories are formed and stored in the brain remains a fascinating question in neuroscience. Here we discuss the memory engram theory, our recent attempt to identify and manipulate memory engram cells in the brain with optogenetics, and how these methods are used to address questions such as how false memory is formed and how the valence of a memory can be changed in the brain. | en_US | 
| dc.description.sponsorship | RIKEN Brain Science Institute | en_US | 
| dc.description.sponsorship | Howard Hughes Medical Institute | en_US | 
| dc.language.iso | en_US |  | 
| dc.publisher | Cold Spring Harbor Laboratory Press | en_US | 
| dc.relation.isversionof | http://dx.doi.org/10.1101/sqb.2014.79.024901 | en_US | 
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US | 
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US | 
| dc.source | Prof. Tonegawa via Courtney Crummett | en_US | 
| dc.title | Identification and Manipulation of Memory Engram Cells | en_US | 
| dc.type | Article | en_US | 
| dc.identifier.citation | Liu, Xu, Steve Ramirez, Roger L. Redondo, and Susumu Tonegawa. “Identification and Manipulation of Memory Engram Cells.” Cold Spring Harbor Symposia on Quantitative Biology 79 (2014): 59–65. | en_US | 
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US | 
| dc.contributor.department | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences | en_US | 
| dc.contributor.department | Picower Institute for Learning and Memory | en_US | 
| dc.contributor.department | RIKEN-MIT Center for Neural Circuit Genetics | en_US | 
| dc.contributor.approver | Tonegawa, Susumu | en_US | 
| dc.contributor.mitauthor | Liu, Xu |  | 
| dc.contributor.mitauthor | Ramirez Moreno, Steve |  | 
| dc.contributor.mitauthor | Redondo Pena, Roger L |  | 
| dc.contributor.mitauthor | Tonegawa, Susumu |  | 
| dc.relation.journal | Cold Spring Harbor Symposia on Quantitative Biology | en_US | 
| dc.eprint.version | Author's final manuscript | en_US | 
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US | 
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US | 
| dspace.orderedauthors | Liu, Xu; Ramirez, Steve; Redondo, Roger L.; Tonegawa, Susumu | en_US | 
| dspace.embargo.terms | N | en_US | 
| dc.identifier.orcid | https://orcid.org/0000-0002-6697-8330 |  | 
| dc.identifier.orcid | https://orcid.org/0000-0003-2839-8228 |  | 
| mit.license | OPEN_ACCESS_POLICY | en_US |