dc.contributor.author | Mou, Shaoshuai | |
dc.contributor.author | Del Vecchio, Domitilla | |
dc.date.accessioned | 2017-04-11T17:32:08Z | |
dc.date.available | 2017-04-11T17:32:08Z | |
dc.date.issued | 2016-02 | |
dc.date.submitted | 2015-12 | |
dc.identifier.isbn | 978-1-4799-7886-1 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/108050 | |
dc.description.abstract | This paper studies how retroactivity impacts the robustness of gene transcription networks against parameter perturbations. By employing the linearization technique and the real stability radius, we provide comparisons of the robustness between gene transcription networks with retroactivity and ones without retroactivity. Both numerical and analytical results show that retroactivity tends to decrease such robustness. This finding in turn implies that modular genetic networks tend to be more robust against parameter perturbations. | en_US |
dc.description.sponsorship | National Science Foundation (U.S.) (NSF-CCF-I058127) | en_US |
dc.language.iso | en_US | |
dc.publisher | Institute of Electrical and Electronics Engineers (IEEE) | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1109/CDC.2015.7402431 | en_US |
dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
dc.source | MIT Web Domain | en_US |
dc.title | How retroactivity impacts the robustness of genetic networks | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Mou, Shaoshuai and Del Vecchio, Domitilla. “How Retroactivity Impacts the Robustness of Genetic Networks.” 2015 54th IEEE Conference on Decision and Control (CDC), December 15-18 2015, Osaka, Japan, Institute of Electrical and Electronics Engineers (IEEE), December 2015. | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Mechanical Engineering | en_US |
dc.contributor.mitauthor | Del Vecchio, Domitilla | |
dc.contributor.mitauthor | Mou, Shaoshuai | |
dc.relation.journal | 2015 54th IEEE Conference on Decision and Control (CDC) | en_US |
dc.eprint.version | Author's final manuscript | en_US |
dc.type.uri | http://purl.org/eprint/type/ConferencePaper | en_US |
eprint.status | http://purl.org/eprint/status/NonPeerReviewed | en_US |
dspace.orderedauthors | Mou, Shaoshuai; Del Vecchio, Domitilla | en_US |
dspace.embargo.terms | N | en_US |
dc.identifier.orcid | https://orcid.org/0000-0001-6472-8576 | |
mit.license | OPEN_ACCESS_POLICY | en_US |
mit.metadata.status | Complete | |