| dc.contributor.author | Ozkumur, Ayca Yalcin | |
| dc.contributor.author | Love, John C | |
| dc.contributor.author | Goods, Brittany A. | |
| dc.date.accessioned | 2017-05-30T19:29:25Z | |
| dc.date.available | 2017-05-30T19:29:25Z | |
| dc.date.issued | 2015-09 | |
| dc.date.submitted | 2015-04 | |
| dc.identifier.issn | 1613-6810 | |
| dc.identifier.issn | 1613-6829 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/109435 | |
| dc.description.abstract | Living-cell-based screens can facilitate lead discovery of functional therapeutics of interest. A versatile and scalable method is reported that uses dense arrays of nanowells for imparting defined patterns on monolayers of cells. It is shown that this approach can coordinate a multi-component biological assay by designing and implementing a high-throughput, functional nanoliter-scale neutralization assay to identify neutralizing antibodies against HIV. | en_US |
| dc.description.sponsorship | National Cancer Institute (U.S.) (P30-CA14051) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Wiley Blackwell | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1002/smll.201500674 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Development of a High-Throughput Functional Screen Using Nanowell-Assisted Cell Patterning | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Ozkumur, Ayca Yalcin; Goods, Brittany A. and Love, J. Christopher. “Development of a High-Throughput Functional Screen Using Nanowell-Assisted Cell Patterning.” Small 11, no. 36 (June 2015): 4643–4650 © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biological Engineering | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemical Engineering | en_US |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
| dc.contributor.mitauthor | Love, John C | |
| dc.contributor.mitauthor | Goods, Brittany A. | |
| dc.relation.journal | Small | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Ozkumur, Ayca Yalcin; Goods, Brittany A.; Love, J. Christopher | en_US |
| dspace.embargo.terms | N | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-0921-3144 | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
