| dc.contributor.author | Sharp, Phillip A. | |
| dc.contributor.author | Wu, Xuebing, Ph. D. Massachusetts Institute of Technology | |
| dc.date.accessioned | 2017-06-02T15:35:45Z | |
| dc.date.available | 2017-06-02T15:35:45Z | |
| dc.date.issued | 2013-11 | |
| dc.identifier.issn | 0092-8674 | |
| dc.identifier.issn | 1097-4172 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/109543 | |
| dc.description.abstract | The mammalian genome is extensively transcribed, a large fraction of which is divergent transcription from promoters and enhancers that is tightly coupled with active gene transcription. Here, we propose that divergent transcription may shape the evolution of the genome by new gene origination. | en_US |
| dc.description.sponsorship | United States. Public Health Service (RO1-GM34277) | en_US |
| dc.description.sponsorship | United States. Public Health Service (R01-CA133404) | en_US |
| dc.description.sponsorship | National Cancer Institute (U.S.) (P30-CA14051) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Elsevier | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1016/j.cell.2013.10.048 | en_US |
| dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs License | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Divergent Transcription: A Driving Force for New Gene Origination? | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Wu, Xuebing and Sharp, Phillip A. “Divergent Transcription: A Driving Force for New Gene Origination?” Cell 155, no. 5 (November 2013): 990–996 © 2013 Elsevier Inc | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Computational and Systems Biology Program | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
| dc.contributor.mitauthor | Wu, Xuebing | |
| dc.contributor.mitauthor | Sharp, Phillip A. | |
| dc.relation.journal | Cell | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Wu, Xuebing; Sharp, Phillip A. | en_US |
| dspace.embargo.terms | N | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-0369-5269 | |
| dc.identifier.orcid | https://orcid.org/0000-0003-1465-1691 | |
| dspace.mitauthor.error | true | |
| mit.license | PUBLISHER_CC | en_US |
