| dc.contributor.author | Zaret, K. S. | |
| dc.contributor.author | Fox, I. J. | |
| dc.contributor.author | Bhatia, Sangeeta N | |
| dc.contributor.author | Underhill, Gregory | |
| dc.date.accessioned | 2017-07-18T16:41:02Z | |
| dc.date.available | 2017-07-18T16:41:02Z | |
| dc.date.issued | 2016-07 | |
| dc.identifier.issn | 1946-6234 | |
| dc.identifier.issn | 1946-6242 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/110764 | |
| dc.description.abstract | Despite the tremendous hurdles presented by the complexity of the liver’s structure and function, advances in liver physiology, stem cell biology and reprogramming, and the engineering of tissues and devices are accelerating the development of cell-based therapies for treating liver disease and liver failure. This State of the Art Review discusses both the near- and long-term prospects for such cell-based therapies and the unique challenges for clinical translation. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (R37 GM36477) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (R01 EB008396) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (UH2 EB017103) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (R01 DK85713) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (RO1 DK48794) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (RO1 DK099320) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (PO1 DK096990) | en_US |
| dc.description.sponsorship | United States. Department of Defense (W81XWH-09-1-0658) | en_US |
| dc.description.sponsorship | United States. Department of Defense ( W81XWH-11-1-0803) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Association for the Advancement of Science (AAAS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1126/scitranslmed.3005975 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Cell and tissue engineering for liver disease | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Bhatia, S. N., G. H. Underhill, K. S. Zaret, and I. J. Fox. “Cell and Tissue Engineering for Liver Disease.” Science Translational Medicine 6, no. 245 (July 16, 2014): 245sr2–245sr2. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Institute for Medical Engineering & Science | en_US |
| dc.contributor.department | Harvard University--MIT Division of Health Sciences and Technology | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science | en_US |
| dc.contributor.mitauthor | Bhatia, Sangeeta N | |
| dc.contributor.mitauthor | Underhill, Gregory | |
| dc.relation.journal | Science Translational Medicine | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Bhatia, S. N.; Underhill, G. H.; Zaret, K. S.; Fox, I. J. | en_US |
| dspace.embargo.terms | N | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0002-1293-2097 | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
