Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans
Author(s)Nakajima, Hideko H.; Farrahi, Shirin; Ghaffari, Roozbeh; Sellon, Jonathan Blake; Freeman, Dennis M.
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Our ability to understand speech requires neural tuning with high frequency resolution, but the peripheral mechanisms underlying sharp tuning in humans remain unclear. Sharp tuning in genetically modified mice has been attributed to decreases in spread of excitation of tectorial membrane traveling waves. Here we show that the spread of excitation of tectorial membrane waves is similar in humans and mice, although the mechanical excitation spans fewer frequencies in humans—suggesting a possible mechanism for sharper tuning.
DepartmentHarvard University--MIT Division of Health Sciences and Technology; Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science; Massachusetts Institute of Technology. Research Laboratory of Electronics
Farrahi, Shirin et al. “Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans.” Biophysical Journal 111, 5 (September 2016): 921–924 © 2016 Biophysical Society
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