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Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans

dc.contributor.authorNakajima, Hideko H.
dc.contributor.authorFarrahi, Shirin
dc.contributor.authorGhaffari, Roozbeh
dc.contributor.authorSellon, Jonathan Blake
dc.contributor.authorFreeman, Dennis M.
dc.date.accessioned2017-09-18T15:10:04Z
dc.date.available2017-09-18T15:10:04Z
dc.date.issued2016-08
dc.date.submitted2016-05
dc.identifier.issn0006-3495
dc.identifier.issn1542-0086
dc.identifier.urihttp://hdl.handle.net/1721.1/111590
dc.description.abstractOur ability to understand speech requires neural tuning with high frequency resolution, but the peripheral mechanisms underlying sharp tuning in humans remain unclear. Sharp tuning in genetically modified mice has been attributed to decreases in spread of excitation of tectorial membrane traveling waves. Here we show that the spread of excitation of tectorial membrane waves is similar in humans and mice, although the mechanical excitation spans fewer frequencies in humans—suggesting a possible mechanism for sharper tuning.en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant R01-DC00238)en_US
dc.language.isoen_US
dc.publisherElsevieren_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.bpj.2016.07.038en_US
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs Licenseen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.sourceElsevieren_US
dc.titleTectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humansen_US
dc.typeArticleen_US
dc.identifier.citationFarrahi, Shirin et al. “Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans.” Biophysical Journal 111, 5 (September 2016): 921–924 © 2016 Biophysical Societyen_US
dc.contributor.departmentHarvard University--MIT Division of Health Sciences and Technologyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Electrical Engineering and Computer Scienceen_US
dc.contributor.departmentMassachusetts Institute of Technology. Research Laboratory of Electronicsen_US
dc.contributor.mitauthorFarrahi, Shirin
dc.contributor.mitauthorGhaffari, Roozbeh
dc.contributor.mitauthorSellon, Jonathan Blake
dc.contributor.mitauthorFreeman, Dennis M.
dc.relation.journalBiophysical Journalen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsFarrahi, Shirin; Ghaffari, Roozbeh; Sellon, Jonathan B.; Nakajima, Hideko H.; Freeman, Dennis M.en_US
dspace.embargo.termsNen_US
dc.identifier.orcidhttps://orcid.org/0000-0003-3369-5067
dc.identifier.orcidhttps://orcid.org/0000-0003-0622-1333
dc.identifier.orcidhttps://orcid.org/0000-0001-6309-0910
dspace.mitauthor.errortrue
mit.licensePUBLISHER_CCen_US


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