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Spatial Charge Configuration Regulates Nanoparticle Transport and Binding Behavior In Vivo

dc.contributor.authorFukumura, Dai
dc.contributor.authorJain, Rakesh K.
dc.contributor.authorHan, Hee-Sun
dc.contributor.authorMartin, John Daniel
dc.contributor.authorLee, Jungmin
dc.contributor.authorHarris, Daniel Kelly
dc.contributor.authorBawendi, Moungi G
dc.date.accessioned2018-01-16T15:44:38Z
dc.date.available2018-01-16T15:44:38Z
dc.date.issued2013-01
dc.date.submitted2012-11
dc.identifier.issn1433-7851
dc.identifier.issn1521-3773
dc.identifier.urihttp://hdl.handle.net/1721.1/113196
dc.description.abstractDetailed arrangements: A new set of zwitterionic quantum dots were synthesized and used to study the influence of microscopic charge arrangements on the in vivo behavior of nanoparticles. Experiments using cultured cells and live mice demonstrate that the microscopic arrangement of surface charges strongly influences nonspecific binding, clearance behavior, and in vivo transport of nanoparticles.en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant U54-CA151884)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant R01-CA126642)en_US
dc.description.sponsorshipInternational Society for Neurochemistry (Award W911NF-07-D-0004)en_US
dc.language.isoen_US
dc.publisherWiley Blackwellen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/anie.201208331en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourcePMCen_US
dc.titleSpatial Charge Configuration Regulates Nanoparticle Transport and Binding Behavior In Vivoen_US
dc.typeArticleen_US
dc.identifier.citationHan, Hee-Sun et al. “Spatial Charge Configuration Regulates Nanoparticle Transport and Binding Behavior In Vivo.” Angewandte Chemie International Edition 52, 5 (December 2012): 1414–1419 © 2013 WILEY-VCH Verlag GmbH & Coen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemical Engineeringen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Materials Science and Engineeringen_US
dc.contributor.mitauthorHan, Hee-Sun
dc.contributor.mitauthorMartin, John Daniel
dc.contributor.mitauthorLee, Jungmin
dc.contributor.mitauthorHarris, Daniel Kelly
dc.contributor.mitauthorBawendi, Moungi G
dc.relation.journalAngewandte Chemie International Editionen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsHan, Hee-Sun; Martin, John D.; Lee, Jungmin; Harris, Daniel K.; Fukumura, Dai; Jain, Rakesh K.; Bawendi, Moungien_US
dspace.embargo.termsNen_US
dc.identifier.orcidhttps://orcid.org/0000-0003-2220-4365
mit.licenseOPEN_ACCESS_POLICYen_US


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