| dc.contributor.author | Feng, Yu-xiong | |
| dc.contributor.author | Sokol, Ethan Samuel | |
| dc.contributor.author | Gupta, Piyush | |
| dc.date.accessioned | 2018-06-22T17:13:00Z | |
| dc.date.available | 2018-06-22T17:13:00Z | |
| dc.date.issued | 2014-10 | |
| dc.date.submitted | 2014-09 | |
| dc.identifier.issn | 2372-3556 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/116526 | |
| dc.description.abstract | In a recent report published in Cancer Discovery we identified a novel vulnerability of cancer cells that have undergone an epithelial–mesenchymal transition (EMT) and established that the PERK branch of the unfolded protein response is constitutively activated upon EMT. In this commentary, we summarize and provide context for our findings. Keywords: EMT; ER stress; UPR | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (Grant 1122374) | en_US |
| dc.publisher | Informa UK Limited | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.4161/23723548.2014.961822 | en_US |
| dc.rights | Creative Commons Attribution-NonCommercial 3.0 Unported | en_US |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc/3.0/ | en_US |
| dc.source | Taylor & Francis | en_US |
| dc.title | The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Feng, Yu-xiong et al. “The Endoplasmic Reticulum May Be an Achilles’ Heel of Cancer Cells That Have Undergone an Epithelial-to-Mesenchymal Transition.” Molecular & Cellular Oncology 1, 2 (June 2014): e961822 © 2014 The Authors | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
| dc.contributor.mitauthor | Sokol, Ethan Samuel | |
| dc.contributor.mitauthor | Gupta, Piyush | |
| dc.relation.journal | Molecular & Cellular Oncology | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2018-06-20T18:28:07Z | |
| dspace.orderedauthors | Feng, Yu-xiong; Sokol, Ethan S; Gupta, Piyush B | en_US |
| dspace.embargo.terms | N | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0002-2988-0537 | |
| dc.identifier.orcid | https://orcid.org/0000-0002-9703-1780 | |
| mit.license | PUBLISHER_CC | en_US |
