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dc.contributor.authorGierut, J. J.
dc.contributor.authorHaigis, K. M.
dc.contributor.authorJacks, Tyler E.
dc.date.accessioned2018-06-25T18:17:27Z
dc.date.available2018-06-25T18:17:27Z
dc.date.issued2014-04
dc.identifier.issn1559-6095
dc.identifier.issn1940-3402
dc.identifier.urihttp://hdl.handle.net/1721.1/116574
dc.description.abstractAlthough the development of improved mouse models, including conditional deletions, marks an exciting time in mouse genetics, it is important to characterize and validate these models. Cre reporter strains allow researchers to assess the recombinase expression profile and function in individual Cre mouse lines. These strains are engineered to express a reporter gene (usually LacZ) following the removal of a floxed STOP cassette, thus marking cell lineages that can be targeted with a given Cre line. This protocol provides a detailed method for the histochemical detection of β-galactosidase activity in Cre mouse strains.en_US
dc.publisherCold Spring Harbor Laboratory Pressen_US
dc.relation.isversionofhttp://dx.doi.org/10.1101/PDB.PROT073452en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourcePMCen_US
dc.titleWhole-Mount X-Gal Staining of Mouse Tissuesen_US
dc.typeArticleen_US
dc.identifier.citationGierut, J. J. et al. “Whole-Mount X-Gal Staining of Mouse Tissues.” Cold Spring Harbor Protocols 2014, 4 (April 2014): 417-419 © 2014 Cold Spring Harbor Laboratory Pressen_US
dc.contributor.departmentKoch Institute for Integrative Cancer Research at MITen_US
dc.contributor.mitauthorJacks, Tyler E.
dc.relation.journalCold Spring Harbor Protocolsen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2018-06-25T16:57:32Z
dspace.orderedauthorsGierut, J. J.; Jacks, T. E.; Haigis, K. M.en_US
dspace.embargo.termsNen_US
dc.identifier.orcidhttps://orcid.org/0000-0001-5785-8911
dspace.mitauthor.errortrue
mit.licenseOPEN_ACCESS_POLICYen_US


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