Cocrystal formation by Ionic liquid-assisted grinding: Case study with cocrystals of caffeine
Author(s)Rogers, Robin D.; Mukherjee, Arijit; Meyerson, A. S.
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iquid assisted grinding using imidazolium-based ionic liquids (IL-AG) was found to be effective in isolation of cocrystals and cocrystal polymorphs. Isolation of specific polymorphs of caffeine–citric acid (CAF–CA) and caffeine–glutaric acid (CAF–GLU) cocrystals highlights the tunability of ILs in polymorphic control.
DepartmentMassachusetts Institute of Technology. Department of Chemical Engineering
Royal Society of Chemistry
Mukherjee, Arijit et al. "Cocrystal formation by Ionic liquid-assisted grinding: Case study with cocrystals of caffeine." CrystEngComm (June 2018) © 2018 Royal Society of Chemistry
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