dc.contributor.author | Hong, Jiyoung A | |
dc.contributor.author | Neel, Dylan V | |
dc.contributor.author | Wassaf, Dina | |
dc.contributor.author | Caballero, Francisco | |
dc.contributor.author | Koehler, Angela Nicole | |
dc.date.accessioned | 2018-09-11T13:50:30Z | |
dc.date.available | 2018-09-11T13:50:30Z | |
dc.date.issued | 2013-11 | |
dc.identifier.issn | 13675931 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/117698 | |
dc.description.abstract | High-throughput and unbiased binding assays have proven useful in probe discovery for a myriad of biomolecules, including targets of unknown structure or function and historically challenging target classes. Over the past decade, a number of novel formats for executing large-scale binding assays have been developed and used successfully in probe discovery campaigns. Here we review the use of one such format, the small-molecule microarray (SMM), as a tool for discovering protein-small molecule interactions. This review will briefly highlight selected recent probe discoveries using SMMs as well as novel uses of SMMs in profiling applications. © 2013 Elsevier Ltd. | en_US |
dc.publisher | Elsevier BV | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1016/J.CBPA.2013.09.020 | en_US |
dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs License | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
dc.source | PMC | en_US |
dc.title | Recent discoveries and applications involving small-molecule microarrays | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Hong, Jiyoung A., et al. “Recent Discoveries and Applications Involving Small-Molecule Microarrays.” Current Opinion in Chemical Biology, vol. 18, Feb. 2014, pp. 21–28. | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Biological Engineering | en_US |
dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
dc.contributor.mitauthor | Koehler, Angela Nicole | |
dc.relation.journal | Current Opinion in Chemical Biology | en_US |
dc.eprint.version | Author's final manuscript | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dc.date.updated | 2018-09-07T15:53:12Z | |
dspace.orderedauthors | Hong, Jiyoung A; Neel, Dylan V; Wassaf, Dina; Caballero, Francisco; Koehler, Angela N | en_US |
dspace.embargo.terms | N | en_US |
mit.license | PUBLISHER_CC | en_US |