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A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings

dc.contributor.authorYesilyurt, Volkan
dc.contributor.authorVeiseh, Omid
dc.contributor.authorDoloff, Joshua C
dc.contributor.authorLi, Jie
dc.contributor.authorBose, Suman
dc.contributor.authorXie, Xi
dc.contributor.authorBader, Andrew R.
dc.contributor.authorChen, Michael Y
dc.contributor.authorWebber, Matthew
dc.contributor.authorVegas, Arturo
dc.contributor.authorLanger, Robert S
dc.contributor.authorAnderson, Daniel Griffith
dc.date.accessioned2019-08-22T15:14:20Z
dc.date.available2019-08-22T15:14:20Z
dc.date.issued2016-12
dc.date.submitted2016-09
dc.identifier.issn2192-2640
dc.identifier.urihttps://hdl.handle.net/1721.1/122007
dc.description.abstractThe surface modification of implantable biomaterials with zwitterionic phosphorylcholine polymer is demonstrated through mussel-mimetic catecholamine polymer thin films. Using this method, the surfaces of alginate hydrogel microspheres and polystyrene microbeads, a model material known to produce robust foreign body responses and fibrosis, are successfully modified to reduce the tissue reaction by reducing the fibrosis in immunocompetent C57BL/6J mice. Keywords: alginate; dopamine; fibrosis; foreign body response; zwitterionic polymersen_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant F32DK101335)en_US
dc.language.isoen
dc.publisherWileyen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/adhm.201601091en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourcePMCen_US
dc.titleA Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatingsen_US
dc.typeArticleen_US
dc.identifier.citationYesilyurt, Volkan et al. "A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings." Advanced Healthcare Materials 6, 4 (December 2016): 1601091 © Wileyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemical Engineeringen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biological Engineeringen_US
dc.contributor.departmentHarvard University--MIT Division of Health Sciences and Technologyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Institute for Medical Engineering & Scienceen_US
dc.contributor.departmentKoch Institute for Integrative Cancer Research at MITen_US
dc.relation.journalAdvanced Healthcare Materialsen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2019-08-09T12:54:12Z
dspace.date.submission2019-08-09T12:54:13Z
mit.journal.volume6en_US
mit.journal.issue4en_US


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