Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer’s Disease

Author(s)
Blanchard, Joel W.; Tsai, Li-Huei; Blanchard, Joel W.
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Abstract
Conflicting clinical studies have reported that statins both reduce and accelerate cognitive impairments in Alzheimer’s disease. In this issue, Van der Kant et al. (2019) use iPSC-derived neurons to thoroughly dissect the link between cholesterol synthesis, phospho-Tau, and amyloid-β, revealing new therapeutic opportunities in Alzheimer’s disease and related dementias.
Date issued
2019-03
URI
https://hdl.handle.net/1721.1/122952
Department
Picower Institute for Learning and Memory
Journal
Cell Stem Cell
Publisher
Elsevier BV
Citation
Blanchard, Joel W. and Tsai, Li-Huei. "Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer’s Disease." Cell Stem Cell 24, 3 (March 2019): 347-349 © 2019 Elsevier
Version: Author's final manuscript
ISSN
1934-5909
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