| dc.contributor.author | Reker, Daniel | |
| dc.contributor.author | Blum, Steven M. | |
| dc.contributor.author | Steiger, Christoph Winfried Johannes | |
| dc.contributor.author | Anger, Kevin E. | |
| dc.contributor.author | Sommer, Jamie M. | |
| dc.contributor.author | Fanikos, John | |
| dc.contributor.author | Traverso, Carlo Giovanni | |
| dc.date.accessioned | 2020-06-18T19:29:01Z | |
| dc.date.available | 2020-06-18T19:29:01Z | |
| dc.date.issued | 2019-03 | |
| dc.date.submitted | 2018-07 | |
| dc.identifier.issn | 1946-6234 | |
| dc.identifier.issn | 1946-6242 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/125869 | |
| dc.description.abstract | Oral forms of medications contain "inactive" ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactions, underscoring the need to maximize the tolerability and safety of medications and their inactive ingredients. | en_US |
| dc.description.sponsorship | National Instutites of Health (Grant EB000244) | en_US |
| dc.language.iso | en | |
| dc.publisher | American Association for the Advancement of Science (AAAS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1126/scitranslmed.aau6753 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | Daniel Reker | en_US |
| dc.title | “Inactive” ingredients in oral medications | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Reker, Daniel et al. '"Inactive" ingredients in oral medications.' Science Translational Medicine 11, 483 (March 2019): eaau6753 © 2019 The Authors | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Mechanical Engineering | en_US |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
| dc.relation.journal | Science Translational Medicine | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2020-06-18T17:50:58Z | |
| dspace.date.submission | 2020-06-18T17:51:03Z | |
| mit.journal.volume | 11 | en_US |
| mit.journal.issue | 483 | en_US |
| mit.license | OPEN_ACCESS_POLICY | |
| mit.metadata.status | Complete | |