| dc.contributor.author | Zhou, Yujing | |
| dc.contributor.author | Engl, Oliver D. | |
| dc.contributor.author | Bandar, Jeffrey | |
| dc.contributor.author | Chant, Emma D. | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2020-07-08T18:50:03Z | |
| dc.date.available | 2020-07-08T18:50:03Z | |
| dc.date.issued | 2018-05 | |
| dc.identifier.issn | 0570-0833 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/126087 | |
| dc.description.abstract | A CuH-catalyzed enantioselective hydroamidation reaction of vinylarenes has been developed using readily accessible 1,4,2-dioxazol-5-ones as electrophilic amidating reagents. This method provides a straightforward and efficient approach to synthesize chiral amides in good yields with high levels of enantiopurity under mild conditions. Moreover, this transformation tolerates substrates bearing a broad range of functional groups. | en_US |
| dc.description.sponsorship | National Institutes of Health (grant nos. GM58160 and GM122483) | en_US |
| dc.language.iso | en | |
| dc.publisher | Wiley | en_US |
| dc.relation.isversionof | 10.1002/ANIE.201802797 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Zhou, Yujing, et al. "CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes." Angewandte Chemie International Edition 57, 22 (May 2018): p. 6672-75 doi 10.1002/ANIE.201802797 ©2018 Author(s) | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.relation.journal | Angewandte Chemie International Edition | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2019-12-12T19:07:59Z | |
| dspace.date.submission | 2019-12-12T19:08:01Z | |
| mit.journal.volume | 57 | en_US |
| mit.journal.issue | 22 | en_US |
| mit.metadata.status | Complete | |
