| dc.contributor.author | Myers, Samuel A. | |
| dc.contributor.author | Wright, Jason | |
| dc.contributor.author | Peckner, Ryan | |
| dc.contributor.author | Kalish, Brian T. | |
| dc.contributor.author | Zhang, Feng | |
| dc.contributor.author | Carr, Steven A | |
| dc.date.accessioned | 2020-07-24T17:47:46Z | |
| dc.date.available | 2020-07-24T17:47:46Z | |
| dc.date.issued | 2018-05 | |
| dc.date.submitted | 2017-12 | |
| dc.identifier.issn | 1548-7091 | |
| dc.identifier.issn | 1548-7105 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/126374 | |
| dc.description.abstract | Regulation of gene expression is primarily controlled by changes in the proteins that occupy genes' regulatory elements. We developed genomic locus proteomics (GLoPro), in which we combine CRISPR-based genome targeting, proximity labeling, and quantitative proteomics to discover proteins associated with a specific genomic locus in native cellular contexts. | en_US |
| dc.language.iso | en | |
| dc.publisher | Springer Science and Business Media LLC | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1038/s41592-018-0007-1 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Discovery of proteins associated with a predefined genomic locus via dCas9–APEX-mediated proximity labeling | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Meyers, Samuel A. et al. "Discovery of proteins associated with a predefined genomic locus via dCas9–APEX-mediated proximity labeling." Nature Methods 15, 6 (May 2018): 437–439 © 2018 The Author(s) | en_US |
| dc.contributor.department | Broad Institute of MIT and Harvard | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
| dc.relation.journal | Nature Methods | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dc.date.updated | 2019-10-08T13:08:42Z | |
| dspace.date.submission | 2019-10-08T13:08:43Z | |
| mit.journal.volume | 15 | en_US |
| mit.journal.issue | 6 | en_US |
| mit.metadata.status | Complete | |
