Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs
Author(s)
Song, Yuelin; van den Berg, Patrick R.; Markoulaki, Styliani; Soldner, Frank; Dall’Agnese, Alessandra; Henninger, Jonathan E.; Drotar, Jesse; Rosenau, Nicholas; Cohen, Malkiel A.; Young, Richard A.; Semrau, Stefan; Stelzer, Yonatan; Jaenisch, Rudolf; ... Show more Show less
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Song et al. used an allelic reporter approach to show super-enhancers allelic DNA methylation dynamics underlies locus-specific heterogeneity, which functionally impacts transcription and cellular states of mouse embryonic stem cells.
Date issued
2019-08Department
Massachusetts Institute of Technology. Department of BiologyJournal
Molecular Cell
Publisher
Elsevier BV
Citation
Song, Yuelin et al. "Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs." Molecular Cell 75, 5 (September 2019): P905-920.e6 © 2019 Elsevier Inc
Version: Author's final manuscript
ISSN
1097-2765