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Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs

dc.contributor.authorSong, Yuelin
dc.contributor.authorvan den Berg, Patrick R.
dc.contributor.authorMarkoulaki, Styliani
dc.contributor.authorSoldner, Frank
dc.contributor.authorDall’Agnese, Alessandra
dc.contributor.authorHenninger, Jonathan E.
dc.contributor.authorDrotar, Jesse
dc.contributor.authorRosenau, Nicholas
dc.contributor.authorCohen, Malkiel A.
dc.contributor.authorYoung, Richard A.
dc.contributor.authorSemrau, Stefan
dc.contributor.authorStelzer, Yonatan
dc.contributor.authorJaenisch, Rudolf
dc.date.accessioned2020-09-21T14:36:44Z
dc.date.available2020-09-21T14:36:44Z
dc.date.issued2019-08
dc.identifier.issn1097-2765
dc.identifier.urihttps://hdl.handle.net/1721.1/127657
dc.description.abstractSong et al. used an allelic reporter approach to show super-enhancers allelic DNA methylation dynamics underlies locus-specific heterogeneity, which functionally impacts transcription and cellular states of mouse embryonic stem cells.en_US
dc.description.sponsorshipNIH (Grants HD045022, 1U19AI131135, 5R01MH104610, and 1R01GM114864)en_US
dc.language.isoen
dc.publisherElsevier BVen_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.molcel.2019.06.045en_US
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs Licenseen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.sourcePMCen_US
dc.titleDynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCsen_US
dc.typeArticleen_US
dc.identifier.citationSong, Yuelin et al. "Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs." Molecular Cell 75, 5 (September 2019): P905-920.e6 © 2019 Elsevier Incen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biologyen_US
dc.relation.journalMolecular Cellen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2020-09-18T18:46:40Z
dspace.date.submission2020-09-18T18:46:43Z
mit.journal.volume75en_US
mit.journal.issue5en_US
mit.licensePUBLISHER_CC
mit.metadata.statusComplete


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