dc.contributor.author | Uhler, Caroline | |
dc.contributor.author | Shivashankar, G. V. | |
dc.date.accessioned | 2021-03-11T21:33:33Z | |
dc.date.available | 2021-03-11T21:33:33Z | |
dc.date.issued | 2020-04 | |
dc.identifier.issn | 1471-0072 | |
dc.identifier.issn | 1471-0080 | |
dc.identifier.uri | https://hdl.handle.net/1721.1/130124 | |
dc.description.abstract | Coronaviruses employ various nuclear signalling mechanisms for their propagation. Here we link replication of coronaviruses, including SARS-CoV-2, the coronavirus disease 2019 (COVID-19)-causing virus, with cytoskeleton-dependent signalling and 3D genome organization. This link could provide novel insights into the high coronavirus pathogenicity in certain cellular states, particularly those associated with ageing. | en_US |
dc.publisher | Springer Science and Business Media LLC | en_US |
dc.relation.isversionof | https://doi.org/10.1038/s41580-020-0242-z | en_US |
dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
dc.source | Prof. Uhler via Phoebe Ayers | en_US |
dc.title | Mechano-genomic regulation of coronaviruses and its interplay with ageing | en_US |
dc.type | Article | en_US |
dc.identifier.citation | Uhler, Caroline and G. V. Shivashankar. "Mechano-genomic regulation of coronaviruses and its interplay with ageing." Nature Reviews Molecular Cell Biology 21, 5 (April 2020): 247–248. © 2020 Springer Nature Limited | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Laboratory for Information and Decision Systems | en_US |
dc.relation.journal | Nature Reviews Molecular Cell Biology | en_US |
dc.eprint.version | Author's final manuscript | en_US |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
dspace.date.submission | 2021-03-05T17:23:36Z | |
mit.journal.volume | 21 | en_US |
mit.journal.issue | 5 | en_US |
mit.license | OPEN_ACCESS_POLICY | |
mit.metadata.status | Complete | |