A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers

Author(s)
Bellan, Leon M.; Pearsall, Matthew; Cropek, Donald M.; Langer, Robert S
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Abstract
3D microfluidic networks are fabricated in a gelatin hydrogel using sacrificial melt-spun microfibers made from a material with pH-dependent solubility. The fibers, after being embedded within the gel, can be removed by changing the gel pH to induce dissolution. This process is performed in an entirely aqueous environment, avoiding extreme temperatures, low pressures, and toxic organic solvents. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Date issued
2012
URI
https://hdl.handle.net/1721.1/134515.2
Department
Koch Institute for Integrative Cancer Research at MIT
Journal
Advanced Materials
Publisher
Wiley
Citation
Bellan, L. M., et al. "A 3d Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers." Adv Mater (2012).
Version: Author's final manuscript
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