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Poly(ethylene glycol) with Observable Shedding
dc.contributor.author | Gao, Weiwei | |
dc.contributor.author | Langer, Robert | |
dc.contributor.author | Farokhzad, Omid C | |
dc.date.accessioned | 2021-10-27T20:05:27Z | |
dc.date.available | 2021-10-27T20:05:27Z | |
dc.date.issued | 2010 | |
dc.identifier.uri | https://hdl.handle.net/1721.1/134534 | |
dc.description.abstract | A FRET-bearing poly(ethylene glycol) (PEG) conjugate fluoresces at 520 nm when it is cleaved off nanoparticles (NPs; see picture). When the NPs were targeted on cancer cell lines, the reducing endosomal environment caused the cleavage of the disulfide bond and the shedding of the PEG layer. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. | |
dc.language.iso | en | |
dc.publisher | Wiley | |
dc.relation.isversionof | 10.1002/anie.201001868 | |
dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
dc.source | PMC | |
dc.title | Poly(ethylene glycol) with Observable Shedding | |
dc.type | Article | |
dc.identifier.citation | Gao, W. W., R. Langer, and O. C. Farokhzad. "Poly(Ethylene Glycol) with Observable Shedding." Angewandte Chemie-International Edition 49 37 (2010): 6567-71. | |
dc.relation.journal | Angewandte Chemie - International Edition | |
dc.eprint.version | Author's final manuscript | |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
eprint.status | http://purl.org/eprint/status/PeerReviewed | |
dc.date.updated | 2019-09-03T18:46:20Z | |
dspace.orderedauthors | Gao, W; Langer, R; Farokhzad, OC | |
dspace.date.submission | 2019-09-03T18:46:21Z | |
mit.journal.volume | 49 | |
mit.journal.issue | 37 | |
mit.metadata.status | Authority Work and Publication Information Needed |