| dc.contributor.author | Wesselhoeft, R Alexander | |
| dc.contributor.author | Kowalski, Piotr S | |
| dc.contributor.author | Parker-Hale, Frances C | |
| dc.contributor.author | Huang, Yuxuan | |
| dc.contributor.author | Bisaria, Namita | |
| dc.contributor.author | Anderson, Daniel G | |
| dc.date.accessioned | 2021-10-27T20:10:42Z | |
| dc.date.available | 2021-10-27T20:10:42Z | |
| dc.date.issued | 2019 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/135094 | |
| dc.description.abstract | © 2019 Elsevier Inc. Wesselhoeft et al. find that exogenous circular RNAs are able to bypass RNA sensors, thereby avoiding antiviral defense induction upon cellular entry. They report that nanoformulated, synthetic protein-coding circRNA can be translated in mouse tissues, providing evidence for the potential of circRNA as a vector for therapeutic gene expression. | |
| dc.language.iso | en | |
| dc.publisher | Elsevier BV | |
| dc.relation.isversionof | 10.1016/J.MOLCEL.2019.02.015 | |
| dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs License | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.source | PMC | |
| dc.title | RNA Circularization Diminishes Immunogenicity and Can Extend Translation Duration In Vivo | |
| dc.type | Article | |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemical Engineering | |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Political Science | |
| dc.contributor.department | Whitehead Institute for Biomedical Research | |
| dc.contributor.department | Massachusetts Institute of Technology. Institute for Medical Engineering & Science | |
| dc.contributor.department | Harvard University--MIT Division of Health Sciences and Technology | |
| dc.relation.journal | Molecular Cell | |
| dc.eprint.version | Author's final manuscript | |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | |
| dc.date.updated | 2021-06-02T18:57:59Z | |
| dspace.orderedauthors | Wesselhoeft, RA; Kowalski, PS; Parker-Hale, FC; Huang, Y; Bisaria, N; Anderson, DG | |
| dspace.date.submission | 2021-06-02T18:58:01Z | |
| mit.journal.volume | 74 | |
| mit.journal.issue | 3 | |
| mit.license | PUBLISHER_CC | |
| mit.metadata.status | Authority Work and Publication Information Needed | |
