Stress Can Induce Transcription of Toxin-Antitoxin Systems without Activating Toxin

Author(s)
LeRoux, Michele; Culviner, Peter H; Liu, Yue J; Littlehale, Megan L; Laub, Michael T
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Abstract
© 2020 Elsevier Inc. The toxin-antitoxin (TA) systems encoded on bacterial chromosomes have long been thought to act as effectors of a cellular stress response system. LeRoux et al. find that, despite strong transcriptional induction following various stress treatments, the toxins of TA systems are not activated under these conditions.
Date issued
2020
URI
https://hdl.handle.net/1721.1/135215
Department
Massachusetts Institute of Technology. Department of Biology; Howard Hughes Medical Institute
Journal
Molecular Cell
Publisher
Elsevier BV
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