Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing
Author(s)
Boyden, Edward
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A high-throughput method for amplication-free single-cell whole-genome sequencing can be scaled up to analyze tens of thousands of cells from different tissues and clinical sample types and identifies replication states, aneuploidies, and subclonal mutations.
Date issued
2019-11-14Department
Massachusetts Institute of Technology. Media LaboratoryJournal
Cell
Publisher
Elsevier BV