Traveling waves in the prefrontal cortex during working memory
Author(s)
Bhattacharya, Sayak; Brincat, Scott L.; Lundqvist, Mikael; Miller, Earl K.
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<jats:p>Neural oscillations are evident across cortex but their spatial structure is not well- explored. Are oscillations stationary or do they form “traveling waves”, i.e., spatially organized patterns whose peaks and troughs move sequentially across cortex? Here, we show that oscillations in the prefrontal cortex (PFC) organized as traveling waves in the theta (4-8Hz), alpha (8-12Hz) and beta (12-30Hz) bands. Some traveling waves were planar but most rotated. The waves were modulated during performance of a working memory task. During baseline conditions, waves flowed bidirectionally along a specific axis of orientation. Waves in different frequency bands could travel in different directions. During task performance, there was an increase in waves in one direction over the other, especially in the beta band.</jats:p>
Date issued
2022-01Department
Picower Institute for Learning and Memory; Massachusetts Institute of Technology. Department of Brain and Cognitive SciencesJournal
PLoS Computational Biology
Publisher
Public Library of Science (PLoS)
Citation
Bhattacharya, Sayak, Brincat, Scott L, Lundqvist, Mikael and Miller, Earl K. 2022. "Traveling waves in the prefrontal cortex during working memory." PLOS Computational Biology, 18 (1).
Version: Final published version
ISSN
1553-7358